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Flibanseriini kehitettiin alun perin masennuslääkkeeksi [3] [4], mutta tutkimukset osoittivat, ettei se ole tässä indikaatiossa lumelääkettä parempi ja sen käyttöä alettiin tutkimaan HSDD:n。

Flibanseriini toimii prefrontaalisella aivoalueella serotoniini 1A -reseptorin agonistina ja 2A-reseptorin antagonistina. Seurauksena on dopamiinin ja noradrenaliinin lisääntyminen ja serotoniinin väheneminen aivojen。

Flibanserin is the first drug to be appflibanseriiniroved for hypoactive sexual desire disorder (HSDD) in premenopausal women by the FDA in August 2015. It was originally developed as an antidepressant medication by Boehringer Ingelheim, but。

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